reinhard stöger  / stoegerlab.com

We introduce immuno-Southern (iSouther n) – a cost-effective lab protocol. By integrating restriction enzyme digestion with antibody detection, iSouthern delivers a dual readout that increases confidence, particularly when evaluating debated DNA modifications such as N6-methyldeoxyadenosine (6mA) in metazoan genomes. Screen first. Sequence later - or independently validate your nanopore / bisulfite sequencing data by iSouthern.

There’s always been uncertainty around N6-methyladenine (6mA) : Is it real in eukaryotes? And if so, what does it actually do? A recent and pretty exciting study from the Mendoza la b finally gives us some answers . It shows that adenine DNA methylation — and the enzyme that writes this modification — can be traced all the way back to the last eukaryotic common ancestor (LECA). Even more interesting, the study finds that 6mA appears to support or enhance transcription

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Chloe successfully defended her PhD thesis: “Molecular and mitochondrial biology of eusocial bees: responses to stress and xenobiotics”...