top of page

about our research

"It's all in the genes" is a common phrase used to explain that a person's traits and predispositions are inherited.

 

We now know that the DNA sequence of an individual does not tell the whole story.

​

Our lab investigates how developmental and environmental factors shape the “epigenome”— the intricate ways in which genes are "programmed" within our cells. A key focus of our research is on DNA modifications that influence gene expression.

Environmental influences play a role in epigenetic programming, especially during critical periods of development. Changes in early life can impact disease risk in adulthood.

We seek to answer important questions such as:
 

  • How stable is epigenetic information, and how fast does it change as we age?

  • How are these processes influenced by developmental and environmental factors?

  • How is epigenetic information passed down through generations via the germ line?

  • In what ways does metabolism impact the epigenome?


To explore these questions, we study a wide range of systems and organisms, ranging from embryonic stem cells, and honey bees to humans.

 

bottom of page